Online advertising is a complex on-line business, which has become the target of abuse. Recent charges filed from the United States Department of Justice against the operators of the DNSChanger botnet stated that the botnet operators stole approximately US$14 million [11,18] over two years. Using monetization tactics similar to DNSChanger, several large botnets (i.e., ZeroAccess and TDSS/TDL4) abuse the ad ecosystem at scale. In order to understand the depth of the financial abuse problem, we need methods that will enable us to passively study large botnets and estimate the lower bounds of their financial abuse. In this paper we present a system, A 2S, which is able to analyze one of the most complex, sophisticated, and long-lived botnets: TDSS/TDL4. Using passive datasets from a large Internet Service Provider in north America, we conservatively estimate lower bounds behind the financial abuse TDSS/TDL4 inflicted on the advertising ecosystem since 2010. Over its lifetime, less than 15% of the botnet’s victims caused at least US$346 million in damages to advertisers due to impression fraud. TDSS/TDL4 abuse translates to an average US$340 thousand loss per day to advertisers, which is three times the ZeroAccess botnet  and more than ten times the DNSChanger botnet  estimates of fraud.